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wo1997035807a1optimization of calcium aluminate for use as a bone

Current Location : Home > wo1997035807a1optimization of calcium aluminate for use as a bone

  • Calcium silicate/calcium aluminate composite biocement for

    calcium aluminate composite biocement for bone restorative application synthesis characterisation and in vitro biocompatibility Advances in Applied Ceramics 115 7 DOI 10.1080

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  • Characterization of Calcium Aluminate Cement Phases when

    2015 18(2) Characterization of Calcium Aluminate Cement Phases when in Contact with Simulated Body Fluid 383 Al 2 O 3-CaO route enabled the production of the target phases (CA CA 2 C 3 A and C 12 A 7) with higher purity compared to the Al 2 O 3-CaCO 3 one in which C stands for CaO and A for Al 2 O 3 15. Therefore in this work in vitro

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  • The Application of Melatonin and Platelet-Rich Plasma in

    DEVELOPMENT OF A BIOACTIVE CALCIUM ALUMINATE BONE REGENERATIVE SCAFFOLD By William P. Clafshenkel Approved July 28 2011 _____ Paula A. Witt-Enderby Ph.D. Professor of Pharmacology-Toxicology Graduate School of Pharmaceutical Sciences Duquesne University Committee Chair _____ Ellen S. Gawalt

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  • Calcium aluminate cement-based blends for application to

    Aug 18 2020 · Calcium aluminate cement CAC has been applied to fill in bone defects. CAC has been used in orthopedics as it can avoid some problems of commercial products polymethylmethacrylate PMMA regarding its too low consistency and strong odor and exothermic reactions which can damage the surrounding tissue.

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  • Novel calcium phosphate composite bone cement strength

    A new high-strength cement prepared from calcium phosphate and calcium aluminate has been developed and was evaluated for potential use in bone and joint repair applications. Cement specimens were aged under simulated physiological conditions. The compressive strength of the cement was determined at time intervals 1 h after setting up to 52 weeks. A compressive strength of 111.6±12.9

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  • Chemical physical and mechanical properties of a novel

    Aug 18 2010 · Results The calcium aluminate cement without additives had a setting time of approximately 60 min and when combined with Li 2 CO 3 it decreased to 10 min. The material also released Ca 2 ions and alkalinized the medium. Moreover the addition of additives (dispersant plasticizer and radiopacifier) improved its properties resulting in a

    Get Price
  • Artificial bone and joint compositions and methods of use

    The use of calcium aluminate (all associated phases derivatives and/or analogs thereof) as a raw material for the manufacture of artificial bone artificial joints in-vitro support structures and support structure for tissue cells and/or organ growth and/or regeneration is provided.

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  • Strength Properties of Calcium Aluminate Ceramics for

    Introduction Calcium aluminate (CA) ceramics have been investigated as a potential synthetic bone graft material 1 2 and a recent study has shown that CA ceramics used with melatonin exhibit excellent osteoconductive and osteoinductive qualities 2 .

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  • Strength Properties of Calcium Aluminate Ceramics for

    Introduction Calcium aluminate (CA) ceramics have been investigated as a potential synthetic bone graft material 1 2 and a recent study has shown that CA ceramics used with melatonin exhibit excellent osteoconductive and osteoinductive qualities 2 .

    Get Price
  • Repair of Bone Defects Filled with New Calcium Aluminate

    The aim of this study was to evaluate and compare the repair of bone defects filled with calcium aluminate cement (EndoBinder) mineral trioxide aggregate (MTA) and calcium hydroxide. Methods After mixing the cements were inserted into bone defects (3.3 mm) mechanically created in the right and left tibias of 30 rats (Rattus norvegicus Wistar).

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  • US Patent Application for CALCIUM ALUMINATE BASED PASTE

    Feb 03 2014 · The present invention relates to a calcium aluminate based paste forming a chemically bonded biomaterial on hydration thereof for in vivo anchoring of new implants or stabilizing of existing implants in situ to an adjacent bone tissue which paste provides a controlled pH value and temperature as well as initial hardening time. By virtue of the pH value and temperature the paste exhibits

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  • Impact of calcium aluminate cement with additives on

    Calcium aluminate-based cement (CAC) represents a promising alternative since it exhibits favorable physicochemical characteristics such as its thermal coefficient of and chemical composition similar to the tooth and human bone 9but also due to the bioactivity i. e. its

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  • Evaluation of Calcium Aluminate/Calcium Phosphate Based

    The curing of calcium aluminate cement occurs with high water consumption during setting and hardening of prepared pastes. The relatively high strength values of calcium aluminate pastes compared to those of calcium phosphate and also wide range variations in the consistency and formulations make it suitable for a wide range of applications 3 4.

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  • New cement based on calcium and strontium aluminates for

    Nov 01 2019 · First the desired crystalline phases of calcium and strontium aluminates i.e. dodeca-calcium hepta-aluminate (Ca 12 Al 14 O 33) C 12 A 7 and tri-strontium aluminate (S 3 Al 2 O 6) S ˇ 3 A were obtained by Solution Combustion Synthesis and characterized.

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  • THE USE OFCERAMICS FOR BONE REPLACEMENT

    andbereplaced inpartorwhole bynewly-formed bone. Ourprevious studies haveshown thatfourdifferent ceramics-alumina calcium aluminate calcium hy-droxyapatite andtricalcium phosphate-are biocompa-tible andthelatter three biodegradable. When these ceramics were implanted incombination with bone marrow intoabdominal muscle sites newly-formed bone

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  • The Application of Melatonin and Platelet-Rich Plasma in

    DEVELOPMENT OF A BIOACTIVE CALCIUM ALUMINATE BONE REGENERATIVE SCAFFOLD By William P. Clafshenkel Approved July 28 2011 _____ Paula A. Witt-Enderby Ph.D. Professor of Pharmacology-Toxicology Graduate School of Pharmaceutical Sciences Duquesne University Committee Chair _____ Ellen S. Gawalt

    Get Price
  • Chemical physical and mechanical properties of a novel

    Aug 18 2010 · Results The calcium aluminate cement without additives had a setting time of approximately 60 min and when combined with Li 2 CO 3 it decreased to 10 min. The material also released Ca 2 ions and alkalinized the medium. Moreover the addition of additives (dispersant plasticizer and radiopacifier) improved its properties resulting in a

    Get Price
  • Novel calcium phosphate composite bone cement strength

    A new high-strength cement prepared from calcium phosphate and calcium aluminate has been developed and was evaluated for potential use in bone and joint repair applications. Cement specimens were aged under simulated physiological conditions. The compressive strength of the cement was determined at time intervals 1 h after setting up to 52 weeks. A compressive strength of 111.6±12.9

    Get Price
  • Synthesis and Characterization of Calcium Aluminate

    Calcium aluminate has been long involved in the practical applications in the cement and concrete industry as well as in refractories and ceramic materials. Recently new advanced applications of calcium aluminate have appeared in optical and structural ceramics. Calcium aluminates (CA)

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  • METHOD OF THERAPEUTIC TREATMENT USING A

    A Method of generating heat in vivo in a patient s body for therapeutical purposes comprising preparing a calcium aluminate mixture having (i) less than 50 vol. but greater than 0 of CA 2 (ii) more than 50 vol. of CA and C 12 A 7 and (iii) less than 10 vol. but greater than 0 of C 3 A adding said calcium aluminate mixture to a

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  • New Calcium Carbonate-Based Cements for Bone

    The feasibility of calcium carbonate-based cements involving the re-crystallization of metastable calcium carbonate varieties has been demonstrated. Two cement compositions were obtained by mixing either calcium carbonate phases (cement A) or a calcium carbonate and a calcium phosphate phase (cement B) with an aqueous media. These cements set and hardened after 30 minutes and 90

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  • A novel calcium aluminate‐melatonin scaffold enhances bone

    Therefore melatonin and platelet‐rich plasma (PRP) were utilized for their known osteoinductive properties. It was hypothesized that melatonin and/or PRP would enhance the osteoinductive and osteoconductive properties of calcium aluminate (CA) scaffolds to promote bone regeneration in a model of calvarial defects.

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  • Porous calcium aluminate ceramics for bone-graft

    Calcium aluminate scaffolds with controlled porosity were processed for bone-graft applications. Indirect fused deposition process was used to fabricate these structures. Phase analyses were done using x-ray diffraction technique on powdered samples of calcium aluminates at different compositions.

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  • Calcium aluminate cement used in bone defects induced in

    The patterns of the calcium aluminate cement in bone defects experimentally induced in the femur of 12 New Zealand White rabbits were evaluated. The animals were distributed in three experimental groups corresponding to postoperative observation periods of 15 (G15) 30 (G30) and 60 (G60) days. Clinical surgical radiographic and histological appraisals were made to observe the osteoinductor

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  • Influence of tricalcium aluminate phase on in vitro

    Influence of tricalcium aluminate phase on in vitro biocompatibility and bioactivity of calcium aluminate bone cement

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  • Strength Properties of Calcium Aluminate Ceramics for

    Introduction Calcium aluminate (CA) ceramics have been investigated as a potential synthetic bone graft material 1 2 and a recent study has shown that CA ceramics used with melatonin exhibit excellent osteoconductive and osteoinductive qualities 2 .

    Get Price
  • METHOD OF THERAPEUTIC TREATMENT USING A

    A Method of generating heat in vivo in a patient s body for therapeutical purposes comprising preparing a calcium aluminate mixture having (i) less than 50 vol. but greater than 0 of CA 2 (ii) more than 50 vol. of CA and C 12 A 7 and (iii) less than 10 vol. but greater than 0 of C 3 A adding said calcium aluminate mixture to a

    Get Price
  • Calcium silicate/calcium aluminate composite biocement for

    (2016). Calcium silicate/calcium aluminate composite biocement for bone restorative application synthesis characterisation and in vitro biocompatibility.

    Get Price
  • USB2Artificial bone and joint compositions and

    The present invention provides a ceramic porous body for in-vitro and in-vivo use comprising a composition comprising a calcium aluminate (CA) containing phase and optionally at least one of an accelerator a retarder a surfactant a foaming agent a reactive alumina water a fiber and a biologically active material and combinations thereof.

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